Good news: In my recent blank measurements there was just nothing – nada – rien – nix. A week before I found some organic species that should not have been there (obviously) – until I noticed that I had used non-acid washed flasks that I had not rinsed properly. A good sign that my cleaning procedure is doing its job.<\/p>\n
I still find column bleeding in the blanks – and in all the samples that I run. That is sometimes a problem for the determination of the peak area – although I observe this overlap rarely. My baseline varies between 2000 and 3000 counts, when scanning a mass range between 15 and 500 amu and a threshold of only 150 counts. So this is not bad at all.<\/p>\n
My guess is that the column is coming to the end of its life (at least for the trace work that I do) and I am currently working on a solution for a new column – together with a separate injector port and and switchbox, just before the effluent is entering the MS; the price of the package will decide, if I can implement this solution. It would keep my column clean and would reduce the number of liner changes significantly.<\/p>\n","protected":false},"excerpt":{"rendered":"
Good news: In my recent blank measurements there was just nothing – nada – rien – nix. A week before I found some organic species that should not have been there (obviously) – until I noticed that I had used non-acid washed flasks that I had not rinsed properly. A good sign that my cleaning … Continue reading Blanks, bleeding and a few more ideas<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-46","post","type-post","status-publish","format-standard","hentry","category-research"],"_links":{"self":[{"href":"http:\/\/www.nomad.priv.at\/researchblog\/index.php?rest_route=\/wp\/v2\/posts\/46","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.nomad.priv.at\/researchblog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.nomad.priv.at\/researchblog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.nomad.priv.at\/researchblog\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.nomad.priv.at\/researchblog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=46"}],"version-history":[{"count":0,"href":"http:\/\/www.nomad.priv.at\/researchblog\/index.php?rest_route=\/wp\/v2\/posts\/46\/revisions"}],"wp:attachment":[{"href":"http:\/\/www.nomad.priv.at\/researchblog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=46"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.nomad.priv.at\/researchblog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=46"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.nomad.priv.at\/researchblog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=46"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}